The solution structure of a class II major histocompatibility complex superantigen binding domain

MJ Jablonsky, PS Subramaniam, HM Johnson… - Biochemical and …, 1997 - Elsevier
We have used 600 MHz 1 H NMR spectroscopy data to determine the solution structure of a
31-residue domain of a murine class II major histocompatibility (MHC) protein. This domain, …

Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen

TS Jardetzky, JH Brown, JC Gorga, LJ Stern, RG Urban… - Nature, 1994 - nature.com
… -binding site of the class Il major histocompatibility complex (… with class I MHC molecules and
this region differs in class I … , by mixing 2 pl protein solution with 2 pl well solution containing …

Direct binding of secreted T-cell receptor beta chain to superantigen associated with class II major histocompatibility complex protein.

NR Gascoigne, KT Ames - Proceedings of the National …, 1991 - National Acad Sciences
… fourth hypervariable region ofVpin superantigen recognition (21… Using a cell-binding assay,
we show here that theisolated p … 50 Al ofa solution (50 pg/ml) and were allowed to bind for 16 …

Molecular docking of superantigens with class II major histocompatibility complex proteins

MA Olson, L Cuff - Journal of Molecular Recognition: An …, 1997 - Wiley Online Library
… thermodynamics found in the crystal and aqueous solution. All of the highest scoring …
structural motif for binding class II major histocompatibility complex molecules. Nature Struct. Biol…

Binding interactions between peptides and proteins of the class II major histocompatibility complex

BJ McFarland, C Beeson - Medicinal research reviews, 2002 - Wiley Online Library
… by the class I and II genes from this genetic region activate T … of the toxic shock syndrome
toxin 1 TSST-1) superantigen to … to an MHC II/peptide complex in solution will actually induce …

Staphylococcal enterotoxins A and B share a common structural motif for binding class II major histocompatibility complex molecules

RG Ulrich, S Bavari, MA Olson - Nature structural biology, 1995 - nature.com
… as superantigens, bind directly to major histocompatibility complex (MHC) class II molecules'…
C) with wild-type or mutant superantigen in Hanks balanced salt solution (HBSS) containing …

[PDF][PDF] Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II

Y Li, H Li, N Dimasi, JK McCormick, R Martin, P Schuck… - Immunity, 2001 - cell.com
binds to the class II 1 domain, SEB and TSST-1 bind … mixing 1 l of complex solution containing
equimolar amounts of This … Major histocompatibility complex class II-associated peptides …

Antigen presentation by major histocompatibility complex class IB molecules

SM Shawar, JM Vyas, JR Rodgers… - Annual review of …, 1994 - annualreviews.org
… " and have defined the natural peptideн binding motif of Qa-2. In addition, significant progress
… The possibility of MHC class II/superantigen recognition was ruled out in this system by …

[HTML][HTML] Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence

K Petersson, M Håkansson, H Nilsson… - The EMBO …, 2001 - embopress.org
… that bind major histocompatibility complex (MHC) class II … belonging to the zinc family share
the zinc‐binding motif with … μl of protein solution with 1.5 μl of well solution containing 0.05 …

[PDF][PDF] Crystal structure of Urtica dioica agglutinin, a superantigen presented by MHC molecules of class I and class II

FA Saul, P Rovira, G Boulot, EJM Van Damme… - Structure, 2000 - cell.com
major histocompatibility complex molecules of class I (MHC-I) or … of the binding of
oligosaccharides to UDA in solution have … contact the class I MHC α2 or the class II MHC β1 …